Treating Hypoxic-Ischemic Encephalopahy With Umbilical Cord Blood Cells

Stem cell therapies have been applied to treat many serious diseases successfully. One of these diseases is hypoxic-ischemic encephalopathy. Hypoxic-ischemic encephalopahy is mainly caused by oxygen deprivation, which leads to brain damage in children. This disease is often associated with several motor impairment and cognitive and developmental disruption during the development period of a child. However a Duke University Medical Center study had shown that stem cell therapy could be beneficial for children with hypoxic-ischemic encephalopathy.

The Duke University research was a pilot study to determine if umbilical cord blood stem cells could improve the condition of the infant, born with symptoms of brain damage. The process must be conducted within the first 14 days after the baby is born. The cord blood was collected from the baby’s own umbilical cord. The primary objective of the research was to see if stem cells could provide a concrete treatment to this condition. Secondly, the scientists would also want to see if the infusion resulted in neurodevelopmental benefits.

The study was launched with 52 children with signs of brain damage in January 2008. It took 9 years to complete the phase 1 of the study. Let’s dig deeper into the research.

The infants, who were enrolled in the study, were in their first 14 postnatal days. And all of them had diagnosed with moderate to severe hypoxic-ischemic encephalopathy. More importantly, all of them have their own umbilical cord blood stored during birth. Infants, who met all these criteria, received four infusions of their own umbilical cord blood stem cells. The dose was determined by the quantity of cord blood, available for the babies. However, the dose for each infusion was 5x10e7 cells/kg. The babies gone through follow up checkups after 4 to 6 and 9 to 12 months. Their MRIs showed significant development.

Another study on the similar subject was published in PubMed – NCBI. This study was also based on autologous umbilical cord blood stem cells to treat hypoxic-ischemic encephalopathy. Children with severe to moderate hypoxic-ischemic encephalopathy were enrolled for this research. All of them had received on autologous umbilical cord blood stem cells. They were given 4 doses of infusion. The team monitored cell infusion characteristics, UCB collection, and pre and post infusion differences. They also compared the hospital outcomes with children, who did not have available stem cells.

After 4 doses of 4.3 mL infusions, the children were examined in order to monitor vital signs. One of the main signs, oxygen deprivation was noticed to be the same pre and post infusion in the first 48 hours. However, the outcome showed significant improvements with a score of >85 later.

So, it’s shown that critical diseases like hypoxic-ischemic encephalopathy can be treated with umbilical cord blood stem cells. However, there are a certain conditions to be fit for the therapy. First of all, your child must have stem cells available for the infusion. So, as a parent, you must consider cord blood banking before your child is born. We sincerely wish you have a healthy pregnancy and a healthy baby. But if something goes wrong, you will always be prepared to tackle the hurdle.

Unravel The Truth of Popular Myths About Hydration

The summer feels awesome after winter being spent curled up under the comfort of the fluffy quilt. Now back on the regular schedule of maintaining a health regimen with the regular walks or run from your sports camp or house. In between, there is no escape from the dehydration.

As we know, 60 percent of the human body is water, and that too is for the wellness of the health. Yet, we see most of the people suffer dehydration, especially the people associated with sports. Much to your surprise, this mere problem as you call it, may lead to diseases like headaches, laxity in exercises, combined with kidney and heart disorders.

It is quite intimidating that when you try to overcome this disorder, you face hurdles. Popular myths about hydration are long discussed. But, it is time to explore how much are they true?

Hydration subsides with a sip of Coffee

Your hydration health deteriorates as you sip the morning cup of coffee. The caffeine in the coffee acts as the killer for your health and leads you to an extreme need to be hydrated. This is what long believed. But, recent study shows that if you can sip caffeinated Joe cup coffee as little as four cups, it does the wonders just like water. As per the expert dietician and nutritionist, as you spend your night-sleeping, your hydration health remains at low-level in the morning. Hence, there is nothing wrong if you want one or two cups of coffee after you get off your bed in the morning. Besides, coffee helps in reducing weight.

Drink Only When You Are Thirsty

Thinking you are well hydrated as you don’t feel thirsty is a wrong perception. Thirst is much like sunburns that is visible when it reaches the level of infinity. Dehydration can impact your health by 2-3% of your body weight prior to the actual thirst acts. It is more relevant to people with older age who measure hydration level with thirstiness.

Gauge the level of well hydrated health by checking the color of your urine. The pale and clear urine symbolizes the better hydrated health while the frequent number of urination every few hours also signals well-hydrated health.

8 Glasses of Water for Every Day

The number cannot guarantee you a well-hydrated health. The needs of every person differ based on age and sex. Apart from these, there are other factors too, such as pregnancy, including that of lactation. Remember, intake of liquid does not always need to be in the form of water. It can come from the food. Plant-based diet is beneficial in this regard. And add to this, fruits and vegetables such as cucumber, watermelon, star fruit and celery can replenish your beverage needs.

Too Much Water is Good

The concentration of electrolytes can be diluted by intake of too much water. As a result, you may face a life-threatening condition for low sodium levels in blood. Balancing electrolytes are important. If you consume more water than your body weight, it could result in death. Hence, manage a well-maintained water intake of only 2-3 cups per hour.

Sports Drinks are Ultimate

Sports drinks contain the goodness of electrolyte properties, helping in preventing tiredness, nausea, spasm in muscles and others. However, remember, this physical condition happens only when you sweat too much for too much physical workout. And this is where you really need a good sport drink. But, just a physical workout for a couple of minutes does not need any kind of sport drinks. And if you still prefer sport drinks to just a plain water, you end up gaining weight.

Dehydration is often assumed as a mere health complication. But, much to your surprise, this highly overlooked health disorder may get you a real headache. If overlooked, serious health complications such as headaches, low blood pressure along with tiredness and even death can occur to you.

Where To Begin On Your Fitness and Health Journey

Going back and forth with where to start on your new healthy adventure can be very frustrating and confusing to the point where a lot of people give up after a week of trying new and different things. My best advice while starting this new adventure is to get in the mind set that everything works differently for everyone! Not every diet will work the same for each person. For example my best friend can only have half the carbohydrates a day than I can because my body can process them faster and distribute it evenly throughout my body. So don’t get frustrated from the beginning because everyone starts out in the same place you are now.

Here I have listed a checklist of things you should consider while starting off on your new adventure of being fit healthy and happy!

Throw out more than half of the junk food in your house, if not all of it.
They are only temptations that we don’t need. Yes you can eat them occasionally but having them linger around gives us more incentive to give into the temptations.

Write a list of your fitness goals.
Start off with writing down your morning weight and date it. Then write down where you want to see yourselves and the time frame you are giving yourself.

Start thinking about meal prep.
Meal prep is all about making meals for your week to get you started on a healthy week because the moment you open that fridge you can grab anything but if you know you already have meals that you prepared you are more willing to go for those and that is always the healthier option.

Go shopping for healthy food options.
You can check out anywhere on the internet for recipes and grocery lists for healthy food options.

Get a gym membership
I know not all of us have a lot of money to spend on expensive over the top gym memberships but there are some gyms like XSport or Planet Fitness that offer $10 memberships and the moment you know you are paying for something you will tend to use it way more often. If this really isn’t a viable option then do at home workouts, take daily walks, start up running or biking riding as a new hobby. It is all about starting off with small changes.

Drink more water.
Your daily water intake should be at least 8 glasses of water a day. This will help with your skin, hair, and overall hunger that we tend to get when we start a diet.

Think of this as a lifestyle change for the better.
The moment we stop calling it a diet is the moment we keep trying for this end goal and we keep up with what we started off doing in the first place.


All About Orthopedic Doctors

An orthopedic doctor is a professional who specializes in bone related conditions.

Situations when you should see the doctor

There are plenty of situations when you should see the doctor. Some of these situations include:

Difficulty performing everyday tasks: It’s common to have joint and bone discomfort especially if you are old; however, if you have been having the discomfort for a long time to the extent that you are unable to execute your daily activities, it’s time to visit the doctor. Some of the tasks that you might be unable to perform include: cleaning the utensils, climbing the stairs, or even sitting.

Chronic pain: You are said to be suffering from chronic pain if have been having the pain for the last 12 weeks. When you have an injury it’s common to have the pain for sometimes, but it shouldn’t last for several weeks. Sometimes the injury might have caused a complication that you should address before it gets worse.

Soft tissue injury that hasn’t improved for two days: If you have fallen or slipped you might have a soft tissue injury. In most cases, soft tissue injuries heal within a matter of hours. If you have an injury and it’s now days and you are still feeling some pain, it’s time to contact a professional who will help you in getting over it.

Instability when walking or standing: A telltale sign that there is something wrong with your joints is feeling shaky or wobbly when performing basic tasks such as walking, sitting, or standing. You should consult a professional who will diagnose the condition and determine the source of the instability.

Reduced range of motion: A reduced range of the movement is a sign of tightening of the joints. It’s also common to have a compromised range of motion when you have arthritis. When the condition has reached a level where the motion is compromised, it’s a high time that you visit a specialist who will diagnose the condition and give you the necessary medications. In some cases, the professional might require you to undertake surgery especially if the situation has brought about a number of complications.

You just had an injury as an athlete: Athletes are known for their high-intensity workouts. If you are a footballer or any other professional and you just had an injury on the field, you shouldn’t ignore it-visit a professional as soon as possible. While the injury might seem simple on the surface, it might have resulted in a number of complications that might put your life in danger.

What to expect from the orthopedic doctor

When you visit the orthopedic physician, there are many things you should expect from him/her. Some of the things include your history. The expert will like to know how you got the injury and how long you have been having the condition. To make the work easy for the doctor, answer the questions as honestly as you can.

The doctor might also want to undertake a number of tests to confirm the extent of the damage. Again you should comply to make the process a success.

The Cellulite Cupping Therapy

The cellulite cups are usually used for therapy referred to as the glide cupping. In such a case, the cups will be moved on the skin. The motion is done across instead of remaining in only one area. So as to make sure that the gliding action is done well and without much effort, oil or cream should be used. Coconut oil may be used, but there are other oils and creams that can aid in the whole cupping therapy.

What are some of the essential oils that can be used during cupping?

There are all kinds of essential oils that you may choose to use for therapy when you are dealing with cellulite. It helps to know the benefits of every so as to make sure that you do settle for the one that is most appropriate for you. Cupping therapy is evolving and anyone who seeks to change the fate of their body by getting rid of cellulite may think about giving it a try. The essential oils for cellulite are:

Grapefruit oil

Grapes have for a long time been closely associated with good diet and this is for very good reasons. The grapes are able to take away all sorts of toxins from the human body and this includes all those synthetic drugs that you may have taken. For people on a prescription, it is important to seek the advice of a doctor before you choose to use the fruit as part of a regimen. Grapefruit oil offers an amazing method of fighting cellulite. You can choose some specific areas and they make sure you massage the location after you dilute with some vegetable oil.

Tangerine oil

Another great oil to use with the cellulite suction cup is tangerine oil. This oil aids in digestion and it greatly improves the circulation of blood which actually helps toxin removal. The aroma also boosts one’s spirits and you find that you can relax better. This makes a great choice when you want to do the cupping therapy.

Cypress oil

When a topical application is done, the circulation is increased. This really helps to make the cellulite work even better since its main aim is to improve circulation in the affected areas. Fluid retention is highly discouraged when this oil is used. This in turn aids in the removal of toxins from the body. Blue cypress is actually anti-inflammatory and it aids the ion flow of blood. Use some vegetable oil to dilute the cypress oil before application. Cypress also helps when you are dealing with varicose veins.

Juniper oil

In history, juniper oil was used as a diuretic and it still is. This is the oil that greatly supports the function of the kidneys. It is able to purify and then assist the natural methods of the detoxification of the body. It also stimulates the digestive system and it is an antiseptic.

Spearmint oil

It is also an antiseptic and anti-inflammatory agent. It is very effective when it is used together with grapefruit especially in areas that have cellulite.